Opinion and Research

Dirk Hanson asked:


We’ve all seen the warnings; the labels on prescription bottles telling us not to mix the pills with alcohol. The warnings tell us that alcohol may blunt or enhance or nullify the effect of the prescribed drugs.

But what’s so bad about mixing alcohol with common medications? What, really, can go wrong? “Nausea and vomiting, headaches, drowsiness, fainting, or loss of coordination,” according to the National Institute on Alcohol Abuse and Alcoholism (NIAAA). “It can also put you at risk for internal bleeding, heart problems, and difficulties breathing. In addition to these dangers, alcohol can make a medication less effective or even useless, or it may make the medication harmful or toxic to your body.”

The NIAAA reminds consumers that certain medicines, such as cough syrup and laxatives, may contain up to 10 per cent alcohol to begin with. Moreover, older people are at particular risk, since the body breaks down alcohol more slowly with age. Woman are also at high risk for drug/alcohol interactions, since blood–alcohol levels are typically higher in women than in men after consuming the same amount of alcohol.

Finally, the NIAAA advises, “Timing is important. Alcohol and medicines can interact harmfully even if they are not taken at the same time.”

Herewith, a partial listing of drug/alcohol reactions to watch out for, taken from the NIAAA’s publication, “Harmful Interactions: Mixing Alcohol with Medicines.”

Possible reactions with alcohol:

–Angina: Isordil, Nitroglycerin. Rapid heartbeat, dizziness, fainting.

–Anxiety and Epilepsy: Librium, Valium, Xanax, etc. Increased risk of overdose, difficulty breathing, impaired motor control, memory problems.

–Blood clots: Coumadin (Warfarin). Internal bleeding, strokes, heart attacks.

–Depression: Prozac, Zoloft, Lexapro, Wellbutrin, etc. Drowsiness, dizziness, increased risk of overdose.

–Diabetes: Glucophage, Orinase, etc. Abnormally low blood sugar, flushing reaction, nausea, vomiting.

–Arthritis: Celebrex, Naprosyn, Voltaren. Ulcers, stomach bleeding, liver problems.

–High blood pressure: Catapres, Cardura, Lopressor, etc. Dizziness, fainting, arrhythmia.

–High cholesterol: Crestor, Lipitor, Pravachol, etc. Liver damage.

–Infections: Acrodantin, Flagyl, Grisactin, Nizoral, Nydrazid, Seromycin, Tindamax: Rapid heartbeat, stomach pain, vomiting, flushing.

–Severe pain: Demerol, Percocet, Vicodin, etc. Drowsiness, dizziness, increased risk of overdose, difficulty breathing, impaired motor control.

–Sleep problems: Ambien, Lunesta, Sominex, etc. Dizziness, difficulty breathing, impaired motor control, memory problems.

–Enlarged prostate: Cardura, Flomax, etc. Dizziness, fainting.

And don’t forget the herbals: Alcohol with Kava Kava may cause liver damage; alcohol with St. John’s Wort risks dizziness and overdose. Chamomile, valerian and lavender will increase drowsiness when mixed with alcohol.



Dr Acai

K Bakhru asked:


It is very essential for everybody to be aware of a detailed account of the attack of major (or grand mal or generalized), focal or Jacksonian and petit mal epilepsies. At times, tests like electroencephalogram (EEG) and / or computed tomographic (CT) scanning may be normal in a case of epilepsy, and, therefore, it is only the evidence of the eyewitness, who is in a position to report the details to the attending physician, when the patient is brol1ght to the hospital. As an emergency case, a clinical diagnosis of epilepsy can be made on the spot. Moreover, such cases/emergencies need immediate treatment, and the tests, even if they are conducted, take their own time.

In major (or grand mal or generalized) epilepsy, after momentarily experiencing a peculiar sensation or feeling, i.e. one of the types of auras, described earlier (the aura may even be absent), the patient loses consciousness instantaneously, and he collapses all at once. And if unluckily, the place is odd, e.g., a patient is coming down the stairs or standing near a fire or on a hill top, he may injure himself badly.

Following the fall, all the muscles of the body, i.e. all the muscles of the limbs, abdomen, chest and even face become rigid/ stiff. Due to the spasm of the trunk/respiratory muscles, breathing almost stops, and as the muscles of the face are also involved, the mouth gets firmly closed, and the teeth get clenched. The patient then experiences acute agony, and is close to death. But within a few seconds, all the muscles relax, breathing is regained, and the patient starts getting convulsions of the whole body, which usually continue for about 1-2 minutes, and thereafter, the whole body gets relaxed or becomes absolutely limp.

During such convulsions, the tongue moves repeatedly inside the mouth, and together with the repeated movements of the jaws, the saliva in the mouth gets stirred, and frothing occurs. The tongue may also be bitten when it comes in-between the teeth, and sometimes bleeding may also occur, causing a blood-stained froth. The patient may pass urine (and rarely faces) during this phase of convulsions. It should be remembered that tongue-bite, frothing, passing of urine are important clinical features of an attack of epilepsy, which must be noticed carefully by the eyewitness, for the information of doctor.

The patient may sleep for hours following an attack. However, he may be awakened after a reasonable time when he may complain of a marked headache and pain in all the muscles. When awake, he may have no recollection of his severe fall or convulsions. At the most, he may remember the aura, i.e. transitory symptoms that he may have experienced before the onset of the attack of epilepsy. However, this information about the aura has a great significance in clinical diagnosis, and, therefore, the patient must be coaxed again and again to elicit the required information.

The patient may even get the attack during sleep, and in such cases, tongue-bite or passing of urine in bed should help in the diagnosis. The patient may even die due to suffocation if he happens to turn over during this nocturnal attack of epilepsy, with his face buried in the pillow.

Attacks of grand mal epilepsy may occur many times a day. However, the occurrence of attacks of epilepsy are quite variable to the extent that the patient may not have any further attack during his/her whole life. And hence the value of mass awareness about the clinical diagnosis of epilepsy increases because the treatment cannot be started when a single/first attack of epilepsy occurs, which remains doubtful due to the lack of evidence. On the other hand, the patient may get one attack after the other without regaining consciousness in between the attacks, called status epilepticus, which could be even fatal, if immediate medical aid is not provided.

At times, there is a transitory jerky movement of the limb / s, so that in case both the lower limbs are involved and the patient is standing, he may fall down all at once. This state is called myoclonic epilepsy. Sometimes the small muscles of face, eyes etc. may also be involved.

In petit mal epilepsy, which occurs often in children, there is an extremely transitory attack of unconsciousness. The child, if standing, does not even fall down, and if he/she is doing his/her home work, the child continues with the work as if he/she has had no interruption. The attack of epilepsy may occur repeatedly even 15, 20, 30 times a day. When the attacks are limited to 1 to 2 per day, or on alternate days or even less, the child may remain unaware of such an attack. And even if he/she brings it to the notice of the parents, it may be ignored altogether.

However, whenever a child brings the attack to the notice of his parents, they. must take it very seriously, and tests like EEG, CT scan etc. should not be delayed. Therefore, the knowledge of symptoms of petit mal epilepsy is most important for parents, and even for teachers in schools, so that the disease may not remain undetected especially in early and occasional cases. However, in rare cases, the child may even collapse during unconsciousness. This is called an akinetic attack/ epilepsy, and thus, in such cases, there is usually no difficulty in diagnosis.

The attacks of petit mal epilepsy may disappear altogether on attaining maturity, although the treatment will have to be commenced as soon as the diagnosis is confirmed.

It is urgent that all persons, particularly all members/ friends/colleagues concerned with the case must keep in mind all the relevant signs and symptoms whenever the patient is to report to the physician for diagnosis.



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Gary Gordon asked:


Hydrotherapy is the use of water for recuperative and healing purposes. Hydrotherapy treatment is largely considered to be the oldest form of medical treatment known to man. Hydrotherapy tubs and other items of hydrotherapy equipment are still used in modern times for a vast range of therapeutic measures.

Hydrotherapy has been used since the dawn of civilization. Evidence of its use can be found in ancient Egyptian, Greek, and Roman societies. Archeological evidence shows that members of the Egyptian ruling class would bathe in waters infused with oils and flowers for rejuvenating effects. Hippocrates, the Greek physician who lived from 460-370 B.C. and recognized as the father of modern medicine, prescribed bathing in spring water to cure illness. Romans built communal baths to promote the general health, hygiene, and well-being of its citizenry. Nonetheless, it wasn’t until the 18th and 19th centuries that it attained its most widespread recognition. Sir John Floyer, an English physician who lived from 1649 to 1734, promoted its benefits. Vincenz Priessnits, an Austrian peasant who lived from 1799-1851, invented sponge baths, douches, and established health spas and hydrotherapy centers in Germany and other European countries. A Dominican monk by the name of Sebastian Kneipp wrote My Water Cure, which was published in 1889. This book was translated into many languages and the benefits of hydrotherapy treatment became widely known throughout Europe and established for the rest of time.

Along with treating diseases and improving wound healing, circulation, relaxation, digestion, and the immune system, hydrotherapy has been proven to be beneficial for people with:

Acne

Anxiety

Arthritis

Asthma

Back Pain

Burns

Chronic Fatigue Syndrome

Constipation

Depression

Headaches

Hyperthermia

Knee Pain

Muscle Pain

Musculoskeletal Disorders

Neck Pain

Sleep Disorders

Sports Injuries

Work-Related Injuries

Varicose Veins

Hydrotherapy treatment also has a soothing effect and calms the lungs, heart, stomach, and endocrine system by stimulating nerve reflexes on the spinal cord.

The recuperative and healing properties of hydrotherapy are commonly known today and the practice is widely used. It reduces stress, revitalizes the circulatory and digestive systems, and decreases sensitivity to pain. Hot water calms and soothes the body, relieving stress and loosening tense muscles. Cold water energizes and stimulates the mind and body and rejuvenates the immune system. Submerging yourself in a hydrotherapy bath tub, or a whirlpool, provides enormous benefits. The whirlpool in a hydrotherapy tank will massage your body, stimulate touch receptors and nerve endings on the skin, boost blood circulation, and release tight muscles. Whirlpools are also used to relieve joint conditions and have been useful in physical therapy for cases of paralysis and stiffness of the extremities.

Recent research has shown that water therapy can be highly curative for a wide range of conditions. For patients who have undergone abdominal surgery, whirlpool therapy can alleviate pain, enhance relaxation, promote pain relief, and assist in wound healing. Whirlpool therapy has been recommended to aid venous circulation and alleviate symptoms for patients with varicose veins. Whirlpool therapy is particularly beneficial for arthritis sufferers. Arthritic patients have shown significant improvement in joint tenderness and in knee range of movement after whirlpool therapy. Water therapy has been recently shown to play a curative role in asthma treatment. Researchers discovered that decreased function of the adrenocortical glands, evidenced by low serum cortisol levels, improved after therapy. This was accompanied by the reduction in the dosage of glucocorticoids needed to control asthma attacks.



Diet Pill

Antony Virgese asked:


Society, ever since its evolution has always regarded sex as a natural act, similar to eating and drinking. Hinduism and Judaism even consider it to be a holy act when performed within the bonds of marriage. The Torah states, “It is not good for men to be alone.” (Gen: 2:18) .Sexual intercourse within marriage is a right and was never a taboo on religious grounds, nor has any government ever interfered in this activity.

Sexual intercourse, as a means for procreation is inherently essential to the continuation of species of any particular generic line. Sexual intercourse is not only a form of pleasure ,but at a higher emotional level sexual intercourse is often ,though not always seen as the ultimate physical expression of feelings of romantic love between two humans.

It is essential therefore for sexual intercourse to be an enjoyable experience .But the reality however is not always so. And on most occasions it is because of the male partner’s inability to have a proper erection for effective penetration. In fact more than half of all men over 40 have difficulties getting or maintaining an erection. This problem also called Erectile Dysfunction (E. D.) occurs when there is a lack of blood flow to the penis. This means that a man can have trouble getting and keeping an erection long enough to have sex. It can happen regularly or once in a while.

However the strong urge among humans to conquer all things desirable, E.D to is no obstacle to an enjoyable sexual experience. The breakthrough in the cure of E.D came in the year 1994, when pharmaceutical giant Pfizer announced the launching of Viagra, as the ultimate medicine for the cure of E.D .Viagra has been hailed as the greatest gift of medical science in the last century.

Viagra hit the market in 1998 and became popular overnight. Cialis and Levitra followed next and according to many is an improvement on Viagra.

Although pills have made life for victims of erectile dysfunction easy its usage is not without side effects. The most common side effects are headache, upset stomach, delayed backache or muscle ache. Although rare, men who experience an erection for more than 4 hours should seek immediate medical attention.



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Lee Dobbins asked:


Over the ages, there have been many theories as to what causes warts with perhaps the most popular being the theory that they come from toads! While toads are a little warty in appearance, rest assured that you cannot get warts by handling them. You can get warts, however from other people that have warts. This is because warts are actually caused by a virus which attacks your skin cells causing them to grow at a faster rate than they should which in turn creates a benign tumor commonly called a wart.

The virus that causes warts is called the human papillomavirus. It can be spread from person to person and it can also spread from one place on your body to another. The virus gets in through breaks in the skin and it thrives in warm moist places so it is often associated with public showers and locker rooms where you would often have skin contact with wet floors where other people have also been walking.

Taking a closer look at what causes warts, one might note that warts could be avoided by always wearing something on your feet at the pool or gym and avoiding sharing personal items with other people such as razors and towels. The interesting thing about the human papilloma virus is that it has an incubation period and can take up to nine months after exposure to actually show up as a wart.

While most anyone can get warts, not everyone does. Some people seem to be more susceptible to them than others. Often younger people under the age of 30 and people with reduced immune function are prone to warts. That’s because warts, being a virus, would have a better chance of settling in on people who were ill-prepared to fight it off. Not everyone who is exposed to the human papillomavirus will get warts because most people have antibodies in their system that will kill off the virus before it can affect their skin cells.

Warts can appear anywhere on your body, but are most often seen on the hands, elbows, knees and ankles. Plantar warts are those found in the bottom of your feet and, while they might be different in appearance than warts and other places they are still the same type of wart just compressed and flattened due to the pressure of walking on them. Genital warts, are an extremely contagious type of wart in the genital area also caused by the human papillomavirus.

So now that you know what causes warts, you’re probably wondering how to get rid of them. There are actually several treatments however, it should be noted, that not every treatment works the same on every one. If you have tried a treatment and it hasn’t worked, don’t feel like you’re “stuck with your warts”, try another treatment until you find one that does work for you. Sometimes warts go away on their own, but if you can wait that long come up with a treatment plan and try many different things until you find something that works effectively for you.



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Sudesh Samuel asked:


Expired medications are commonplace and inertia notwithstanding, many of us tend to rely on an intuitive sense of their value in continuing to store and use them. Such drugs can be harmful to health in several ways; they can be unpredictable in effectiveness, simply ineffective, or even toxic.

 

The formal way of classifying a medication as having expired is through it’s labeled expiry date. This date is often set based on a combination of the common properties of the dosage form as well as the stability and expiration studies of the product that have been conducted by the manufacturer. Importantly, this expiry date is contingent on specific storage conditions of the product. Although a medication may pass it’s labeled expiry date, it may not necessarily be any less effective or dangerous to consume depending on the product itself, the storage conditions and the circumstances leading up to expiry.

 

When most medications pass their expiry date under appropriate storage conditions, they are generally taken to have become so variable in effectiveness as to have become unsuitable for use. This often comes about as a result of the degradation of the active ingredients of the medication with exposure to physical, chemical or microbiological variables like temperature, pressure, humidity, light, bacteria as well as other components of the product known as excipients.

 

Creams may “crack” once their expiry date is passed, leading to a separation of the components and hence provide a non-uniform delivery of active ingredients. This can lead to the poor control of conditions like eczema or acne. Tablet medications can mechanically “powder” off, change in consistency with exposure to water vapor or even experience the contained drug itself becoming ineffective on prolonged exposure to air as occurs with glyceryl trinitrate, an emergency medicine that can easily become ineffective in relieving acute symptoms of chest pain. With common injections, should the acidity change to fall outside a fairly narrow range, significant pain and tissue damage can result from use. With most eye drops, an expiry date of one month after opening is accepted to minimize the potential for dangerous bacterial contamination.

 

With any medication, once a specific threshold of remaining active ingredient is passed, the medication can no longer be relied upon to deliver accurate doses. This loss of reliability is often exacerbated by the fact that the active ingredients can degrade into various combinations of active, inactive or toxic breakdown products. The common aspirin is for instance, known to react with moisture to breakdown into salicylic acid, which is active, and acetic acid, which is inactive and can lead to toxicity in excess.

 

While the expiry date provides a useful gauge of when to stop using a medication, there are also many other factors that can informally accelerate the expiry of a medication and make it dangerous to use, chief among which is how the medication is stored. It is oftentimes not just the medication that is affected by storage conditions but also the storage container. Under inappropriate storage conditions, certain containers can leech material into liquid medication preparations, or medication particles can stick to the container rather than remain separated. On average, a 10 degree rise in temperature doubles the rate of chemical reactions that occur to a medication product and can accelerate the rate of bacterial contamination several fold. Just like an ice cream can simply melt or a loaf of bread becomes mouldy much quicker if not refrigerated, many medication products can easily expire much faster when not stored appropriately.

 

With oral liquid and topical medications, potentially dangerous changes associated with expiry can at times be detected by color or consistency changes, component separations, altered smell or taste (oral preparations). Should a suspicion of expiry arise, a medication expert should be consulted regardless of whether or not the labeled expiry date has been passed.

 

“Expiry” should also be understood to occur once a supply of medications is no longer used appropriately for it’s intended purpose. Consultation with a medication expert is always advised to prevent the inappropriate use of existing medication supplies. Inappropriate use can often occur with self-medication and is harmful. An unfinished supply of a previously used antibiotic may be tried to treat a new infection that is actually untreatable by or resistant to that antibiotic. This practice may not only delay recovery but can also encourage the proliferation of “super bugs” that have resistance to many antibiotics. Another incorrect purpose involves sharing medications and this can be especially harmful if another is allergic to the shared medication or a child or pet is medicated with an adult’s medication. Children often require dose adjustments to accommodate their size while many human drugs are often unsuitable for pets. Even a simple food like chocolate that we may enjoy can easily be toxic to a pet dog.

 

Another mechanism whereby medication expiry is dangerous occurs when an unfinished supply is used despite new information that points to increased precautions associated with the medication or that has led to it’s recall. An example is obtaining pain relief from a previous supply of a painkiller like Vioxx (rofecoxib) or Celebrex (celecoxib) in spite of an existing heart condition that is now known to relate to an increased risk of fatality under those circumstances of consumption.

 

Expired medications that are kept instead of discarded not only take up space but can actually discourage the appropriate use of new supplies in the treatment of illness. A medication cabinet, if not tended to regularly, could eventually contain more expired medications than viable ones and this can lead to the accidental consumption of an expired medication in place of a viable one. It is definitely advisable to clear the medication cabinet of expired medicaitons at least annually if not more often.

 

A further danger however, lies in how expired medications are disposed of. Expired medications and pharmaceutical byproducts can be harmful to the environment especially when they end up in our rivers and drinking water supply. Hormonal compounds like estrogen from birth control pills and patches as well as antibiotics have been linked to being flushed by individuals and institutions into sewage, draining largely unchanged and collecting in rivers and streams, then returning in tiny amounts into drinking water. Traces of antibiotics could worsen bacterial resistance while estrogens and other steroids are known to change the reproductive characteristics of fish. Even trace amounts of chemotherapy medications have emerged in tap water and this could be severely detrimental to the unborn babies of pregnant women who drink such water. The long-term impact on human health of medications in our rivers and drinking water is as yet unknown but no one would want to wait to find out. We can all play our part by inquiring on and using pharmacy or state-run programs for the disposal of expired medications instead of sending them down the sink or the toilet bowl.

 

A pharmacist is the expert of choice to approach in handling medication expiry and should be consulted if in doubt. As a general rule, it is always best to safeguard your own health and that of those around you by expeditiously and appropriately discarding all expired medications.



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Paul Moss asked:


Lasik surgery is a surgical technical aiming at correcting vision of people who are nearsighted, farsighted or have astigmatism. There are divergent points of view on the matter. Patients needing LASIK surgery often think that they will never eye glass or contact one day. It is obvious that more than the majority of patients undergoing LASIK surgery do present an improvement of their vision after the surgery unfortunately other patients are not that happy. Therefore some patients may still need eyeglasses or contact after the surgery. Some patients even revealed a worse vision after undergoing the surgery than before. As a rule of thumb, you should always not have high expectations of LASIK.

It is believed that Lasik will be of great help to many patients. Indeed, patients undergoing Lasik encountered an improvement factor of a minimum of 20/40 in their vision. Unfortunately, this figure is not always true as there are some cases where patients should be wary of. Therefore, before deciding to undergo LASIK surgery, you should always do a lot of research background on the subject in order to make sure that you fully understand what you are heading to.

There are some positive statistics about Lasik surgery though. A survey revealed that up to 94 percent of all Lasik patients are happy with the results and present an improvement factor of at least 20/20 after the surgery. According to the same survey, nearly all patients were suggested to undergo Lasik by their friends. The same survey shows that 25 percent of patients with problems experience during the surgery could have been sorted out with a good warming-up before the surgery actually takes place. Lasik is also believed not to vision of farsighted or nearsighted patients if they are more than forty. Twenty five percent of patients were reported to have night vision problems after the surgery. These were sorted out within a few months.

Although Lasik is one of the easiest surgeries in medicine, patients should be aware of its expectations before undergoing the surgery. For instance, it is common to see patients undergoing the surgery with no knowledge of the recovery time. The healing time, on the other hand, is quite fast, but you should not fasten your seat belt before two hours. Your doctor is very likely to advise you not to drive by a week after undergoing the surgery. Another recommendation is the inability to go to work by four days after the surgery. Although Lasik is generally a harmless surgery, some patients encounter a pain on their eye shortly after the surgery.

Furthermore, patients undergoing Lasik should look after themselves after the surgery. Meeting your doctor frequently in order to monitor the progress is an essential part of the process. Always make sure that you keep taking any drugs that were giving to you by the doctor in order to get the best result from the surgery. Your doctor should be able to give you specific advice about any drug that was recommended to you. You should also note that there may be a break in sport activities following the Lasik surgery.

Should you not fully understand risks of the Lasik surgery and have realistic expectations of it, please do not undergo the surgery. Before deciding to undergo the surgery make sure it is the right option available to you. Many patients showing poor results after the surgery were not prone to the Lasik surgery. You should discuss in depth the matter with your doctor. Do not hide any details about your eye condition over the past because these can be crucial.

Before deciding to undergo the surgery you should ask yourself this question: am I a good candidate for the Lasik procedure?

Qualifications of a good candidate for Lasik include the following:

- Women who are not pregnant due to the high number of hormone variations during pregnancy

- Significant health or eye problems. These include diabetes, hepatitis.

Briefly speaking, many patients can benefits from Lasik surgery provided they do not have high expectations beforehand. They should understand that it is not a miracle surgery and is therefore prone to some drawbacks. Lasik can help people with poor vision. Remember to double check with your doctor if you are a good candidate for Lasik before heading to the operation room.



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Edwin Stubbs asked:


As a result of advancement of technology researchers and practitioners have managed to manufacture drug for almost all kinds of diseases. Drugs for curing dangerous diseases like AIDS are already under trial. But along with these drugs comes hefty bills which often put unbearable pressure on your pocket. The costs of drugs have reached such a level that even the hospitals find it difficult to bear the cost spend on branded drugs. An alternative in the form of Generic drugs in available for such people.

In the current scenario generic equivalent of most drugs are easily available including infamous anti-impotency drugs like Apcalis, Tadalis, Tadalafil and Cheap Generic Cialis. These drugs come at much lower prices as compared to their branded equivalents. Moreover, their ingredients as well as effectiveness are exactly the same. As a result people who are suffering from sexual disorders like erectile dysfunction prefer to buy generic drugs like Kamagra, Penegra and Generic Viagra over branded viagra.

Erectile dysfunction or ED is a problem related to men’s sexuality under which he is unable to hold hard penis erection for some time or completely fails to get any hardness. This ruins his sex life as he becomes ineligible to indulge in most treasured possession of human sexuality, that is, sexual intercourse. In such a state he becomes more prone to problems like depression and distress. Treatments are available in many forms which only lead to confusion and conflicts in the mind of poor ED patient.

One tries to avoid complicated procedures like penis surgery or getting his penis injected. With advent of, already discussed, highly expensive branded anti-impotency drugs like viagra and cialis going for générique de Drogue is the most feasible option available to these individuals to bring that much needed zest into their sex lives. People often buy anti-ED drugs from generic cialis pharmacy after all they are smart enough to a make the right choice both in terms of drugs as well as pharmacies.



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Krishan B Kumar asked:


As the disease advances, various systems/organs of the body start deteriorating due to the collection of poisons/toxins in the body, which the diseased kidneys cannot excrete fully.

The patient complains of marked loss of appetite, nausea and recurrent vomiting (especially in the morning). These are the early symptoms, and the patient may report only with these vague complaints, and at such a stage, it is only the clinician who can clinch the diagnosis, provided the patient reports to him well in time.

The taste of the mouth gets altered. A marked ulceration may follow in the mouth as well as in the stomach and/ orintestine, leading to haemorrhage in both the stomach and the intestine, causing–vomiting of blood (haematemesis) or the passing of blood in stools (melaena). There is a marked pain in the abdomen and the patient usually reports as a case of bleeding peptic ulcer. Loss of fluids, as a result of vomiting/ haemorrhage, further deteriorates kidney functions as a result of dehydration. Hiccoughs are another symptom as the disease progresses.

In addition, blood pressure rises as a result of the damage to the kidneys, called ‘renal hypertension’. Sometimes, the patient may be already suffering from high blood pressure, which may have contributed to the injury to the kidneys. Further, heart failure may occur due to the persistent elevation of blood pressure. In advanced cases, the pericardium, i.e. the membrane covering the heart may also be involved (pericarditis) .

Fall in haemoglobin (chronic anaemia) becomes a constant feature of CRE As the blood urea/serum creatinine rises, haemoglobin falls accordingly, and both are so corelated that even an estimation of haemoglobin, which is a simple test, can indicate the progress of the disease. The fall in haemoglobin occurs due to the toxic effect on the bone marrow, which gets depressed, as well as due to haemorrhages in the stomach/ intestine, etc. Anaemia is difficult to treat as the patient cannot tolerate oral iron due to constant nausea, vomiting and ulceration in the gastrointestinal tract.

Soon the lungs may be affected, and the patient may experience difficulty in breathing (uraemic lungs).

In the same way, the bones may be affected (renalosteodystrophy), and, likewise, the peripheral nerves may be involved (neuropathy), and there may develop a marked weakness in the muscles (myopathy), and a number of other conditions like muscle twitches / tremors etc. may show up.

The brain or the central nervous system may be involved, leading to drowsiness and even coma. CRF or uraemia is one of the important causes of coma:

Sometimes epilepsy/epileptic fits may also manifest itself. Epilepsy may be the only presenting signal of CRF, i.e. the patient can present himself as a case of epilepsy, and if blood ureal serum creatinine estimation is done, his blood urea may be as high as 400 mg/ dl, and likewise there will be a higher level of serum creatinine. Although such cases are not common, the estimation of blood urea/serum creatinine in all cases of epilepsy may prove rewarding, in excluding advanced cases of CRF.

There may also occur high levels of blood uric acid (hyperuricaemia), as a result of blood uric acid not being excreted by the kidneys fully. This results in the various complications of high blood uric acid. Marked itching (pruritus) of the whole body adds to the misery of the patient, and it hardly responds to any treatment.

Hence, as a result of CRF, almost every part of the body gets significantly involved, threatening the life of the patient.



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K. Purdenn asked:


Rough skin growth that resembles blister and usually found in moist surroundings in our bodies is the popularly known wart. It is highly contagious that it not just disseminates on your own body but could also spread to other bodies. It can be transferred to other bodies when there are mainly close body contacts like when you engaged to sexual intercourse, or by letting contaminated persons use your own things that you usually also use in your own personal hygiene.

Why don’t try various natural wart removals? Instead of administering to modern treatments that could leave you wounds, scars, and other negative effects. Aside from those externally bad effects after engaging to modern techniques, the treatments are expensive and could cost a lot.

Below are the versatile instructions of natural wart removal. This is easy to do that it will not waste any of the time you have given to cure naturally and effectively your warts.

? Mash a raw piece of garlic clove and put it in your wart. Cover it with bandage or any other unsoiled cloth. Leave it there for consecutive seven days.

? Extract from the dandelion stem the milky liquid and apply onto your wart. Do this once to twice a day.

? Grind a tablet of vitamin C and put it to your wart. Cover with bandage to compress. Just repeat every day until the wart fall of.

? Various fruits such as grapes, pineapples, and bananas are known to have conjugated proteins that can eliminate warts. You could just drop the extracts of these fruits in a bandage and cover it then to your infected skin. Another choice is to tape the banana peel directly to the wart. Replace it three times a day every morning and every night. Repeat the procedure until the wart would be gone.

? Simply apply drops of honey on your wart every morning and evening. Repeat it everyday until the wart is preparing to fall of and be gone.

? Cook cabbage in a boiling water. After cooling it in a few minutes after it was cooked, place in on your wart for five minutes, only once a day. Do it for about two days and your wart would magically disappear.

? Scrub a slice of potato to your wart more than once a day. Do this for weeks until your warts are deciding to pass out of sight.

? In a study showed, a significant success in curing harmless warts is by using Chinese herbs. You have to grind the herbs into fine paste and applied it to your wart for 15 minutes once a day.

Why people are turning to natural wart removal? Reasons are because natural wart removal is not ambiguous so there should be no fear about having scars. It is comparatively inexpensive and would respect any of your desired privacies. There would not also be bad side effects because, from the description itself, it is natural. Above all, natural wart removal promises to give or recompense no recurrence of the warts after the process, and the permanent outcome. Natural wart removal is truly the most effective and fastest way of removing warts.



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